CryoEM Thermo Fisher Scientific Workshop: Cryo-electron microscopy: An indispensable solution for Structural Biology
Time: 1:15 pm - 2:45 pm
Cryo-EM – Single Particle Analysis (SPA) in particular - has rapidly developed from a pioneering into a mainstream application that has caused a revolution in the field of structural biology at the atomic resolution. Significant resolution improvements on 3D protein structures and their interactive states have led to an increasing insight in protein machineries, sub-cellular interactions and mechanisms. This will eventually contribute to answer real biologically as well as medically relevant questions.
The results that have recently been obtained and published have triggered a large group of new users – mostly originating from the field of X-ray crystallography and NMR – to adopt cryo-EM as a viable, complementary technology. Now, finally, a continuum has been reached on all important aspects with regards to resolution and macromolecular scales which allows for the full deployment of the combination of these technologies.
We will discuss the future of structural biology based on the latest developments of the Thermo Fisher Scientific cryo-EM workflows and their components.
Thermo Fisher Scientific
BIO: Dr. Wim Voorhout studied Biochemistry at Utrecht University and after obtaining his PhD in Electron Microscopy in 1988 did a 4 year post-doc at the Utrecht Medical School on protein trafficking. In 1992 he became an assistant professor at the Department of Biochemistry and Head of the Imaging Facility at the School of Veterinary Medicine in Utrecht. In 2000 he joined FEI Company, a leading manufacturer of Electron Microscopes, as a senior Application Scientist with a focus on Cellular and Structural Biology and in 2006 became head of the TEM Application Laboratory. After several positions in Product Marketing and Application Development he is currently a global Business Development manager with a strong focus on cryo-EM for Structural Biology.
Monash University, Australia
Cryo-electron microscopy: An indispensable solution for Structural Biology abs#300