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Research Fellow Position

Molecular Biologist position available in the Wilce Laboratory

A position is available for a post-doctoral scientist to commence immediately in the Wilce Structural Biology Laboratory at Monash University, Melbourne (Clayton Campus) for NHMRC funding studies of protein-RNA interactions.

The selected applicant will be primarily involved in “Defining poly-C-binding protein stabilised RNA structures essential for viral genome translation and replication”. This project is to delineate protein/RNA structures that are required for picornavirus genome translation and replication. The applicant would also be involved in other ongoing projects.

Suitable applicants will have very strong foundations in the preparation of protein for biophysical characterisation (including molecular biological techniques for the cloning of new constructs, protein expression, purification and quality control). They will also, ideally, have experience in the preparation of RNA for biophysical experiments and analysis of protein/RNA interactions (using SHAPE, hydroxyl radical analysis and RNAase footprinting techniques). They should also have experience in X-ray crystallographic or imaging techniques and biophysical techniques for the characterisation of molecular interactions such as SPR, ITC, AUC and/or fluorescence anisotropy.

The selected applicant will be part of a team of post-doctoral researchers and students and be expected to work collegially with the team and to assist in the supervision of more junior members. They will also be responsible for paper writing, regular presentations and assistance with grant proposal preparation.

Salary will be commensurate with experience.

Position may be applied for via (Job No. 568080)

Enquiries should be directed to A/Prof Jackie Wilce <>

Closing date: 23rd November 2017